The number of cases of breast implant-associated anaplastic large-cell lymphoma increased to 457, according to the FDA.
An artificial intelligence-derived prediction model achieved the best accuracy yet for distinguishing between high- and low-risk prostate cancer. (Scientific Reports)
Immune checkpoint inhibitors appeared to be safe and effective for patients with cancer and HIV infection. (Georgetown Lombardi Comprehensive Cancer Center, JAMA Oncology)
The U.S. Preventive Services Task Force continued to recommend against screening for pancreatic cancer in asymptomatic adults.
Efforts to reduce lung cancer mortality paid off in England with an estimated 500,000 fewer deaths than would have been projected in 1979 from then-current trends. (Cancer Research UK)
The CAR T-cell therapy tisagenlecleucel (Kymriah) passed muster with England's cost-effectiveness agency, which recommended the therapy for adults with relapsed/refractory diffuse large B-cell lymphoma. (NICE)
A study of children and young adults conceived by assisted reproduction showed no increased risk of cancer. (The Netherlands Cancer Institute, Human Reproduction)
Rates of obesity-related cancers increased among young adults, with a trend toward cancer onset at younger ages. (The Lancet Public Health)
A silver lining for chocolate lovers: The health-related news isn't all bad. (American Cancer Society)
More evidence that stereotactic radiotherapy may help improve survival in stage IV lung cancer. (University of Pittsburgh, ASTRO)
The adverse effects of cancer therapy on bones needs more attention, recognition, research, and preventive strategies. (British Journal of Clinical Pharmacology)
MacroGenics said its investigational agent margetuximab improved progression-free survival compared with trastuzumab (Herceptin) in a phase III trial involving patients with metastatic HER2-positive breast cancer.
NoxoPharm announced favorable results from a preliminary trial of its radiotherapy-enhancing agent idronoxil (Veyonda) in prostate cancer.
Xrays: FDA report claims women with breast implants mayomadacycline Non-Inferior in CABP, Skin Structure Infections
FDA Actions, we continue to collect and evaluate information about alcl in individuals with breast implants. Before getting breast implants, make sure to talk to your health care provider about the benefits and risks of both textured-surface and smooth-surfaced implants. What factors should I nephrotic Syndrome: A Hindrance to Lupus Treatment? consider when deciding between different breast reconstruction options? Though BIA-alcl is rare, its important that women familiarize themselves with the symptoms, how we diagnose and treat the disease, and the health follow-up guidelines we recommend if you choose to get breast implants after breast cancer surgery. If you have breast implants, there is no need to change your routine medical care and follow-up. When BIA-alcl does occur, it almost always can be cured. Treatment for...
The French National Agency for Medicines and Health Products Safety (ansm) asked manufacturers of textured breast implants to perform biocompatibility testing (testing to determine how living tissues react to textured implants) and to report their findings. It is important to recognize the symptoms and see your plastic surgeon should they occur. Report all confirmed cases of alcl in individuals with breast implants to the FDA through MedWatch, the FDA Safety Information and Adverse house Hearing on ACA Lawsuit Gets Heated Event Reporting program. Study findings: As of February 1, 2017, the has received 359 medical device reports, including 9 deaths, of breast implant-associated anaplastic large cell (alcl 203 cases involved textured implants; 28 involved smooth implants.