Apomorphine spc



Your doctor prinivil nursing considerations or nurse will administer apomorphine for you to begin with. If you have any questions about this medicine ask your pharmacist. However, extra caution is recommended during initiation of therapy in elderly patients because of the risk of postural hypotension. 4.6 Pregnancy and lactation Pregnancy There is no experience of apomorphine usage in pregnant women.

Uncommon: Apomorphine may induce dyskinesias during 'on' periods, which can be severe in some cases, and in a few patients may result in cessation of therapy. Any unused solution should be discarded. You may be shown how to use injections at home. Parkinson's disease is a disorder of the brain. Skip the missed dose if it is almost time for your next scheduled dose. Do not inject apomorphine into a vein.

4.7 Effects on ability to drive and use machines Apomorphine HCl has minor or moderate influence on the ability to drive and use machines. Small lumps, tenderness and redness at the injection site. Neuropsychiatric problems co-exist in many patients with advanced Parkinson's disease. 6.6 Special precautions for disposal and other handling APO-go PFS 5 mg/ml Solution for Infusion in Pre-filled generic cialis india 8th Syringe is for single use only. You may need to restart with a lower dose. A small part of the brain, called the substantia nigra, is mainly affected.

SPC -PIL : mhra



Treatment with apomorphine will be started while you are in hospital or in a specialist clinic. In effect, it acts like a substitute for dopamine. bradycardia may be treated with atropine. Seek emergency medical attention or call the Poison Help line. Ask your doctor or nurse for further advice. The possible effects of apomorphine on the plasma concentrations of other medicinal products have not been studied.

APO-go Pen injections are for injections which are given intermittently throughout the day, whereas APO-go PFS injections are for when apomorphine is being given as a continuous infusion through a syringe driver. Important Information, serious drug interactions can occur when certain medicines are used together with apomorphine. Only clear, colourless and particle fee solution should be used. Discard your used pens, syringes or needles in a 'sharps bin' after use and arrange for safe disposal. If you have a heart condition or a blood vessel disorder. Type of medicine, dopamine-receptor agonist, used for, parkinson's disease.

Dopamine dysregulation Syndrome (DDS) is an addictive disorder resulting in excessive use of the product seen in some patients treated with apomorphine. The patient should be supervised by a physician experienced in the treatment of Parkinson's disease (e.g. Talk with your doctor if this occurs. Read all patient information, medication guides, and instruction sheets provided to you.

Apomorphine, wikipedia Republished / wiki

In vitro genotoxicity studies demonstrated mutagenic and clastogenic effects, most likely due to products formed by oxidation of apomorphine. Before you use an injection, check to make sure that the liquid is clear and doesn't contain any floating 'bits'. The metabolism of apomorphine is by glucuronidation and sulphonation to at least ten per cent of the total; other pathways have not been described. Call your doctor at once if you have: nausea or vomiting that continues after taking an anti-nausea medication; twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs; worsening of your Parkinson symptoms; a light-headed feeling.

This class of medicine is in the list of drugs included in regulations under 5a of the Road Traffic Act 1988. It may later be reduced or slowly withdrawn. Date of revision of the text 22 February 2018 Company contact details Britannia Pharmaceuticals Limited Address 200 Longwater Avenue, Green Park, Reading, Berkshire, RG2 6GP, UK Telephone Medical Information e-mail WWW Medical Information Direct Line 44 (0) Bookmark. Skip to main content, start typing to retrieve search suggestions.

4.8 Undesirable effects Very common (1/10) Common (1/100 to 1/10) Uncommon (1/1,000 to 1/100) Rare (1/10,000 to 1/1,000) Very rare ( 1/10,000) Not known (cannot be estimated from the available data) Blood and lymphatic system disorders Uncommon: Haemolytic anaemia and thrombocytopenia. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). This area of the brain sends messages down nerves to control the muscles of your body. Method of Administration APO-go PFS 5 mg/ml Solution for Infusion in Pre-filled Syringe is a pre-diluted pre-filled syringe intended for use without dilution as a continuous subcutaneous infusion by minipump and / or syringe-driver. Common apomorphine side-effects, what can I do if I experience this?

 

Apomorphine for Parkinson's disease - APO-go Patient

The management of elderly patients treated with APO-go has not differed from that of younger patients. Investigations Uncommon: Positive Coombs' tests have been reported for patients receiving apomorphine. Paediatric population, aPO-go PFS 5 mg/ml Solution for Infusion in Pre-filled Syringe is contra-indicated for children and adolescents under 18 years of age (see Section.3). Tell your doctor if the medicine seems to stop working as well.

See also: Gocovri, apomorphine has some of the same effects as a chemical called dopamine, which occurs naturally in your body. If you have any mental health problems, such as psychosis or dementia. Also medication possibly affecting electrolyte balance, CYP3A4 metabolism or QT interval should be assessed. Selection of Patients Suitable for APO-go injections: Patients selected for treatment with APO-go should be able to recognise the onset of their 'off' symptoms and be capable of injecting themselves or else have a responsible carer able to inject for them when required. Treatment for...

Not all pack sizes may be marketed. When prescribing this medicine, patients should be told: - The medicine is likely to affect your ability to drive - Do not drive until you know how the medicine affects you - It is an offence to drive. Do not take any anti-nausea medicine without first asking your doctor. Take them to your local pharmacy which will dispose of them for you. Each APO-go Pen can be used for up to 48 hours. 4.5 Interaction with other medicinal products and other forms of interaction Patients selected for treatment with apomorphine HCl are almost certain to be taking concomitant medicinal products for their Parkinson's disease.