Skelaxin pill

An overdose of metaxalone can be fatal. Doubling the dose of skelaxin from 400 mg to 800 mg results in a roughly proportional increase in metaxalone exposure as indicated by peak plasma concentrations (Cmax) and area under the curve (AUC). Consultation with a regional poison control center is recommended. How should I take metaxalone (Skelaxin)? It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Before taking this medicine, you should not use Skelaxin if you are allergic to metaxalone, or if you have: anemia (low red blood cells severe kidney disease; or severe liver disease. Compared to fasted conditions, the presence of a high fat meal at the time of drug administration increased C by 193.6 and increased AUC (AUC0-t, AUC) by 146.4 and 142.2, respectively. Post marketing experience has not revealed evidence of fetal injury, but such experience cannot exclude the possibility of infrequent or subtle damage to the human fetus. Known tendency to drug induced, hemolytic, or other anemias. Serotonin syndrome has been reported when metaxalone was used at doses higher than the recommended dose (see warnings ). Table 2: Mean (CV) Pharmacokinetic Parameters Following Single Administration of Two 400 mg skelaxin Tablets (800 mg) under Fasted and Fed Conditions Age (years) Younger Volunteers Older Volunteers. N Food Fasted Fed.

Hepatic/Renal Insufficiency The impact of hepatic and renal disease on the pharmacokinetics of metaxalone has not been determined. Treatment Gastric lavage and supportive therapy. Skelaxin (metaxalone) is available as an 800 mg oval, scored pink tablet. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Nursing Mothers It is not known whether this drug is secreted in human milk. Precautions Metaxalone should be administered with great care to patients with pre-existing liver damage.

Skelaxin (Metaxalone Side Effects, Interactions, Warning, Dosage

Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures. To make sure Skelaxin is safe for you, tell your doctor if you have liver or kidney disease. Multi ingredient medications may also be listed when applicable. Similar findings were also seen when the previously described combined dataset was used in the analysis. Tell any doctor who treats you that you are using this medicine.

Overdosage Contraindications overdose Deaths by deliberate or accidental overdose have occurred with metaxalone, particularly in combination with antidepressants, and have been reported with this class of drug in combination with alcohol. Serial liver function studies should be performed in these patients. Skelaxin may also be used for purposes not listed in this medication guide. Metaxalone is metabolized by the liver and excreted in the urine as unidentified metabolites. Side Effects what are the early symptoms of cancer in men? Drug Interactions, sIDE effects, the most frequent reactions to metaxalone include: CNS: drowsiness, dizziness, headache, and nervousness or irritability; Digestive: nausea, vomiting, gastrointestinal upset. What should I avoid while taking metaxalone (Skelaxin)?

Be careful if you drive or do anything that requires you to be awake and alert. Do not drink alcohol. Dizziness or drowsiness may be more likely in older adults. (See clinical pharmacology : Pharmacokinetics and patient information ). Similar food effect results were observed in the above study when one skelaxin 800 mg tablet was administered in place of two skelaxin 400 mg tablets. Available in bottles of 100 (.

Skelaxin, oral : Uses, Side Effects, Interactions, Pictures, Warnings

You should not use Skelaxin if you have anemia (low red blood cells or severe kidney or liver disease. Take Skelaxin exactly as it was prescribed for you. Get emergency medical help if you have signs of an allergic reaction to Skelaxin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop paying too much for your prescriptions. Where can I get more information (Skelaxin)? The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. NDC ) and in bottles of 500 (. What other drugs will affect Skelaxin? What are the possible side effects of metaxalone (Skelaxin)? Get emergency medical help if you have signs of an allergic reaction: hives ; difficult breathing; swelling of your face, lips, tongue, or throat. Due to the potential for SS, caution is advised when metaxalone is co-administered with drugs that may affect the serotonergic neurotransmitter systems, such as tramadol or ssris (see warnings ).

Drug interactions The sedative effects of skelaxin and other CNS depressants (e.g., alcohol, benzodiazepines, opioids, tricyclic antidepressants ) may be additive. Metaxalone does not directly relax tense skeletal muscles in man. Distributed by: Pfizer Inc., New York, NY 10017. Using the combined data, the results indicate that the pharmacokinetics of metaxalone are significantly more affected by age under fasted conditions than under fed conditions, with bioavailability under fasted conditions increasing with age. Signs of SS may include clonus, agitation, diaphoresis, tremor, hyperreflexia, hypertonia, and temperature elevation. Skelaxin may enhance the effects of alcohol and other CNS depressants.


Skelaxin : Uses, Dosage Side Effects

Return to, pill Identifier, results for "Skelaxin c 86 62 1 /3 86 67 S 1 /4. Back Pain Slideshow: Myths and Facts. Significantly impaired renal or hepatic function. This medicine may impair your thinking or reactions. Time-to-peak concentration (Tmax) was also delayed (4.9 h versus.0 h) and terminal half-life was decreased (4.2 h versus.0 h) under fed conditions compared to fasted conditions. Figure 1: Mean (SD) Concentrations of Metaxalone following an 800mg Dose under Fasted and Fed Conditions Distribution, Metabolism, And Excretion Although plasma protein binding and absolute bioavailability of metaxalone are not known, the apparent volume of distribution.

The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone is a muscle relaxant. Metaxalone is only part of a complete treatment program that may also include rest, physical therapy, or other pain relief measures. Hepatic Cytochrome P450 enzymes play a role in the metabolism of metaxalone. Warnings Precautions warnings Serotonin syndrome (SS which is potentially life-threatening, has been reported with metaxalone use. If you are currently a resident of the United States, please reach out at and let us know. Treatment for...

Stop using metaxalone and call cancer doctor shortage ’puts care at risk’ your doctor at once if you have: weak or shallow breathing; a light-headed feeling, like you might pass out; pale or yellowed skin, dark colored urine, fever, confusion or weakness; or upper stomach pain. Safe use of metaxalone has not been established with regard to possible adverse effects upon fetal development. What happens if I overdose (Skelaxin)? Dangerous side effects or death can occur when alcohol is combined with metaxalone. Drug interactions No information provided.